Resistenz gegen Reserveantibiotikum entdeckt: Sind Antibiotika bald wirkungslos?

Resistenz gegen Reserveantibiotikum entdeckt: Sind Antibiotika bald wirkungslos?

von Natur Total

Vor zwei Jahren haben chinesische Forscher ein Gen entdeckt, das Darmbakterien gegen das Reserveantibiotikum Colistin immun macht. Mittlerweile konnte das Gen auch in Deutschland nachgewiesen werden. Besonders brisant: Das Gen springt leicht auf andere Bakterienstämme. Daher besteht die Gefahr von Supererregern, gegen die kein Antibiotikum mehr hilft.


Reserveantibiotika haben meist schwere Nebenwirkungen. Sie kommen erst zur Anwendung, wenn besser verträgliche Mittel versagt haben. Doch dann sind sie die letzte Hoffnung. Umso gefährlicher ist es, wenn Krankheitserreger gegen ein Reserveantibiotikum resistent werden.

Nicht nur Tiere betroffen
In China entdeckten Forscher 2015 bei Untersuchungen an Schweinen Darmbakterien, die gegen das Reserveantibiotikum Colistin immun sind. Verantwortlich für die Resistenz ist ein MCR-1 genanntes Gen, das die Hülle der Bakterienzellen so verändert, dass das Antibiotikum nicht mehr daran andocken kann.
Die Entdeckung einer Colistin-Resistenz bei Nutztieren ist nicht erstaunlich, zumal Colistin in der Veterinärmedizin - anders als in der Humanmedizin - sehr verbreitet ist. Allein in Deutschland bezogen Tierärzte 2016 fast 70 Tonnen des Antibiotikums. Aufhorchen lässt indes, dass das Resistenzgen auch bei Menschen gefunden wurde. In 16 von 1322 Krankenhausproben, die sie analysierten, konnten die chinesischen Wissenschaftler MCR-1 nachweisen.

Gefahr von Superkeimen
Dabei handelt es sich keineswegs um ein rein chinesisches Problem. So fand ein Forscherteam der Universität Gießen und des Deutschen Zentrums für Infektionsforschung das Gen in einer deutschen Patientenprobe. Die Forscher machten eine weitere beunruhigende Entdeckung: Das MCR-1-Gen verbreitet sich viel leichter zwischen unterschiedlichen Bakterienarten, als bisher angenommen.
Dadurch können Krankheitserreger, die schon gegen verschiedene Antibiotika unempfindlich sind, zusätzlich eine Immunität gegen Colistin aufbauen. Das ist bereits geschehen. Neben einer Colistin-Resistenz fand sich bei der Gießener Probe eine Immunität gegen Carbapeneme. Dies ist besorgniserregend, denn Colistin ist die letzte Behandlungsoption, wenn Carbapeneme, die ebenfalls zu den Reserveantibiotika gehören, nicht wirken.
Bei gesunden Menschen sind Bakterien, die das MCR-1-Gen tragen - meist handelt es sich um harmlose Darmbakterien - normalerweise nicht gefährlich. Gefährlich wird es erst, wenn sie in Organe gelangen, in denen sie nichts zu suchen haben, und dort eine Infektion verursachen. Gefahr kann paradoxerweise auch von einer unspezifischen Antibiotikabehandlung ausgehen: Die Medikamente töten nicht-resistente Krankheitserreger ab, wodurch sich die resistenten Keime besser vermehren können und zur Bedrohung werden.

Regierung will Antibiotikaverbrauch eindämmen
Die deutsche Regierung hat 2015 eine Strategie zur Bekämpfung von Antibiotikaresistenzen beschlossen. Sie will den Antibiotikaverbrauch verringern - in der Humanmedizin ebenso wie in der Tiermedizin. Daneben fördert sie die Entwicklung neuer Antibiotika. Außerdem soll die Hygiene im Gesundheitswesen verbessert werden. Immerhin sterben jedes Jahr zwischen 10.000 und 15.000 Menschen an Krankenhausinfektionen.
In der Tiermedizin zeigen die Anstrengungen, den Verbrauch von Antibiotika einzuschränken, Wirkung. Von 2011 bis 2016 ging die abgegebene Menge um 56,5 Prozent von 1.706 auf 742 Tonnen zurück. Im selben Zeitraum nahm der Antibiotikaverbrauch in der Humanmedizin um 4,3 Prozent auf 368 Millionen definierte Tagesdosen zu. Schleppend verläuft auch die Entwicklung neuer Medikamente. Seit 2011 sind laut dem Verband forschender Arzneimittelhersteller gerade einmal sechs neue Antibiotika auf den Markt gekommen, die Problemkeimen den Garaus machen sollen.

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Create one here", "forgot": "Forgot password", "all_collection": "All Collections", "world_wide_delivery": "Worldwide delivery", "shipping_text": "Free UK Delivery on orders over £ 100", "hot_line": "Hot line" }, "menu": { "mobile_menu_tab": "Menu", "mobile_account_tab": "Account", "mobile_settings_tab": "Settings" }, "slideshow": { "next_slide": "Next slide", "previous_slide": "Previous slide", "pause_slideshow": "Pause slideshow", "play_slideshow": "Play slideshow", "play_video": "Play video", "close_video": "Close video" }, "map": { "get_directions": "Get directions", "address_error": "Error looking up that address", "address_no_results": "No results for that address", "address_query_limit_html": "You have exceeded the Google API usage limit. Consider upgrading to a Premium Plan<\/a>.", "auth_error_html": "There was a problem authenticating your Google Maps account. Create and enable the JavaScript API<\/a> and Geocoding API<\/a> permissions of your app." } }, "blogs": { "article": { "view_all": "View all", "all_topics": "All topics", "by_author": "by [[ author ]]", "posted_in": "Posted in", "read_more": "Read more", "back_to_blog": "Back to [[ title ]]" }, "comments": { "title": "Leave a comment", "name": "Name", "email": "Email", "message": "Message", "post": "Post comment", "moderated": "Please note, comments must be approved before they are published", "success_moderated": "Your comment was posted successfully. We will publish it in a little while, as our blog is moderated.", "success": "Your comment was posted successfully! Thank you!", "comments_with_count": { "one": "[[ count ]] comment", "other": "[[ count ]] comments" } } }, "cart": { "general": { "title": "Your cart", "note": "Add a note to your order", "remove": "Remove", "subtotal": "Subtotal", "savings": "You're saving", "shipping_at_checkout": "Shipping & taxes calculated at checkout", "update": "Update", "checkout": "Process Check out", "empty": "Your cart is currently empty.", "cookies_required": "Enable cookies to use the shopping cart", "edit": "Edit", "cancel": "Cancel", "continue_shopping": "Continue shopping", "recently_added_item": "Recently added item(s)", "remove_item": "Remove This Item", "view_and_edit_cart": "View and edit cart", "clear": "Clear cart", "empty_page_title": "Shopping Cart is Empty", "here": "here", "empty_continue_html": "Click here to continue shopping.", "processing": "Processing...", "items_count_label" : "[[ count ]] item(s) in your cart", "ok" : "Ok" }, "label": { "product": "Product", "price": "Price", "quantity": "Quantity", "total": "Total", "total_item": "Total item", "sub_total_top": "Cart Subtotal" } }, "collections": { "general": { "view_all": "View all", "clear_all": "Clear All", "no_matches": "Sorry, there are no products in this collection", "items_with_count": { "one": "[[ count ]] product", "other": "[[ count ]] products" }, "load_more": "Load More", "sidebar_btn": "Filter by" }, "sorting": { "title": "Sort by", "manual": "Featured", "best_selling": "Best Selling", "title_ascending": "Alphabetically, A-Z", "title_descending": "Alphabetically, Z-A", "price_ascending": "Price, low to high", "price_descending": "Price, high to low", "created_descending": "Date, new to old", "created_ascending": "Date, old to new" }, "filters": { "title_tags": "Filter", "all_tags": "All products", "categories": "categories", "title": "Filter", "color": "Color", "size": "Size", "brand": "Brand", "price": "Price", "green": "Green", "blue": "Blue", "red": "Red", "pink": "Pink", "black": "Black", "purple": "Purple", "white": "White", "orange": "Orange" }, "product_item": { "quick_shop": "Quick View", "compare": "Compare", "wishlist": "Add to Wishlist" } }, "contact": { "form": { "name": "Name", "email": "Email", "phone": "Phone Number", "message": "Message", "submit": "Submit", "post_success": "Thanks for contacting us. We'll get back to you as soon as possible.", "address": "Address", "telephone": "Telephone", "title": "Write us", "required": "Required" } }, "customer": { "account": { "title": "My Account", "details": "Account Details", "view_addresses": "View Addresses", "return": "Return to Account Details" }, "activate_account": { "title": "Activate Account", "subtext": "Create your password to activate your account.", "password": "Password", "password_confirm": "Confirm Password", "submit": "Activate Account", "cancel": "Decline Invitation" }, "addresses": { "title": "Your Addresses", "default": "Default", "add_new": "Add a New Address", "edit_address": "Edit address", "first_name": "First Name", "last_name": "Last Name", "company": "Company", "address1": "Address1", "address2": "Address2", "city": "City", "country": "Country", "province": "Province", "zip": "Postal\/Zip Code", "phone": "Phone", "set_default": "Set as default address", "add": "Add Address", "update": "Update Address", "cancel": "Cancel", "edit": "Edit", "delete": "Delete", "delete_confirm": "Are you sure you wish to delete this address?" }, "login": { "title": "Login", "desc": "If you have an account, sign in with your email address.", "email": "Email", "password": "Password", "forgot_password": "Forgot your password?", "sign_in": "Sign In", "guest_title": "Continue as a guest", "guest_continue": "Continue" }, "orders": { "title": "Order History", "order_number": "Order", "date": "Date", "payment_status": "Payment Status", "fulfillment_status": "Fulfillment Status", "total": "Total", "none": "You haven't placed any orders yet." }, "order": { "title": "Order [[ name ]]", "date": "Placed on [[ date ]]", "cancelled": "Order Cancelled on [[ date ]]", "cancelled_reason": "Reason: [[ reason ]]", "billing_address": "Billing Address", "payment_status": "Payment Status", "shipping_address": "Shipping Address", "fulfillment_status": "Fulfillment Status", "discount": "Discount", "shipping": "Shipping", "tax": "Tax", "product": "Product", "sku": "SKU", "price": "Price", "quantity": "Quantity", "total": "Total", "fulfilled_at": "Fulfilled [[ date ]]", "subtotal": "Subtotal" }, "recover_password": { "title": "Reset your password", "email": "Email", "submit": "Submit", "cancel": "Cancel", "subtext": "We will send you an email to reset your password.", "success": "We've sent you an email with a link to update your password." }, "reset_password": { "title": "Reset account password", "subtext": "Enter a new password for [[ email ]]", "password": "Password", "password_confirm": "Confirm Password", "submit": "Reset Password" }, "register": { "title": "Create Account", "first_name": "First Name", "last_name": "Last Name", "email": "Email", "password": "Password", "submit": "Create", "desc": "Creating an account is easy. Just fill in the form below." } }, "homepage": { "onboarding": { "product_title": "Your product's name", "product_description": "This area is used to describe your product’s details. Tell customers about the look, feel, and style of your product. Add details on color, materials used, sizing, and where it was made.", "collection_title": "Your collection's name", "blog_title": "Your post's title", "blog_excerpt": "Your store hasn’t published any blog posts yet. A blog can be used to talk about new product launches, tips, or other news you want to share with your customers. You can check out Shopify’s ecommerce blog for inspiration and advice for your own store and blog.", "blog_author": "Author name", "no_content": "This section doesn’t currently include any content. Add content to this section using the sidebar." } }, "layout": { "navigation": { "search": "Search", "toggle": "expand\/collapse", "expand": "expand", "collapse": "collapse", "all_categories": "All Categories" }, "cart": { "title": "Cart", "items_count": { "one": "item", "other": "items" } }, "customer": { "account": "Account", "log_out": "Log out", "logout": "Log out", "log_in": "Log in", "create_account": "Create account", "sign_up": "Sign up", "wishlist": "Wishlist" }, "footer": { "social_platform": "[[ name ]] on [[ platform ]]" }, "list_page": { "grid": "Grid", "list": "List" } }, "products": { "product": { "regular_price": "Regular price", "sold_out": "Sold out", "unavailable": "Unavailable", "on_sale": "Sale", "quantity": "Quantity", "add_to_cart": "Add to cart", "back_to_collection": "Back to [[ title ]]", "related_title": "Related Products", "qty_increase": "Increase", "qty_decrease": "Decrease", "deal_days": "Days", "deal_hours": "Hours", "deal_minutes": "Minutes", "deal_second": "Second", "select_option": "Select Option", "add_to_wishlist": "Add to Wishlist", "add_to_review": "Add to review", "compare_success_msg": "[[ product_title ]] has added to comparing box successful", "compare_exist_msg": "[[ product_title ]] is exist in comparing box", "compare_cart_msg": "[[ product_title ]] has added to shopping cart", "compare_remove_msg": "[[ product_title ]] has removed from comparing box", "compare_remove_msg": "[[ product_title ]] has removed from comparing box", "comparing_box": "Comparing box", "compare_no_items": "There is no items in comparing box", "wishlist_success_msg": "[[ product_title ]] has added to wishlist successful", "wishlist_exist_msg": "[[ product_title ]] is exist in wishlist", "wishlist_cart_msg": "[[ product_title ]] has added to shopping cart", "wishlist_box": "Wishlist", "wishlist_remove_msg": "[[ product_title ]] has removed from wishlist", "wislist_no_items": "There is no items in wishlist", "share": "Share product", "share_on_facebook": "Share on Facebook", "share_on_twitter": "Share on Twitter", "share_on_pinterest": "Share on Pinterest", "share_on_google": "Share on Google+", "share_on_linkedin": "Share on LinkedIn", "availability": "Availability", "in_stock": "In Stock", "out_of_stock": "Out of stock", "quick_overview": "Quick Overview", "details": "Details", "reviews": "Reviews", "first_review": "Be the first review", "tags": "Product Tags", "size_chart": "Size Chart", "options": "Options", "vendor": "Vendor", "features": "Features", "sale_left_text": "[[ sales ]] SOLD. HURRY! ONLY A FEW LEFT!", "checkout_text": "Secured and trusted checkout with" }, "upsell": { "recommend_text": "Someone purchased a", "minute_ago": "minutes ago" } }, "gift_cards": { "issued": { "title_html": "Here's your [[ value ]] gift card for [[ shop ]]!", "subtext": "Your gift card", "disabled": "Disabled", "expired": "Expired on [[ expiry ]]", "active": "Expires on [[ expiry ]]", "redeem_html": "Use this code at checkout to redeem your [[ value ]] gift card", "shop_link": "Start shopping", "print": "Print this gift card", "remaining_html": "[[ balance ]] left", "add_to_apple_wallet": "Add to Apple Wallet" } }, "date_formats": { "month_day_year": "%B %d, %Y" } }, "fr":{ "general": { "field": { "required": "Requis", "actions": "Les actes", "top_btn": "Haut" }, "accessibility": { "skip_to_content": "Passer au contenu", "close_modal": "Fermer (Esc)" }, "meta": { "tags": "Mots clés \"[[ tags ]]\"", "page": "Page [[ page ]]" }, "404": { "title": "404 - Page non trouvée", "subtext": "Cette page n'est pas disponible.", "link": "Retourner au magasinage" }, "pagination": { "previous": "Précédent", "next": "Suivant", "current_page": "Page [[ current ]] sur [[ total ]]" }, "password_page": { "opening_soon": "Bientôt ouvert", "login_form_heading": "Accéder à la boutique à l'aide d'un mot de passe", "login_form_password_label": "Mot de passe", "login_form_password_placeholder": "Votre mot de passe", "login_form_submit": "Entrer", "signup_form_email_label": "Courriel", "signup_form_success": "Nous vous ferons parvenir un courriel juste avant l'ouverture!", "admin_link_html": "Êtes-vous le propriétaire de la boutique? Connectez-vous ici<\/a>.", "password_link": "Entrer avec un mot de passe", "powered_by_shopify_html": "Cette boutique sera propulsée par [[ shopify ]]" }, "social": { "share_on_facebook": "Partager", "share_on_twitter": "Tweeter", "share_on_pinterest": "Épingler", "alt_text": { "share_on_facebook": "Partager sur Facebook", "share_on_twitter": "Tweeter sur Twitter", "share_on_pinterest": "Épingler sur Pinterest" } }, "search": { "no_results_html": "Votre recherche pour \"[[ terms ]]\" n'a pas généré de résultats.", "results_with_count": { "one": "[[ count ]] résultat pour \"[[ terms ]]\"", "other": "[[ count ]] résultats pour \"[[ terms ]]\"" }, "title": "Effectuez une recherche", "placeholder": "Recherche", "submit": "Recherche", "close": "Fermer (esc)" }, "newsletter_form": { "newsletter_email": "Join our mailing list", "email_placeholder": "Adresse courriel", "confirmation": "Merci pour votre abonnement", "submit": "S'inscrire", "show_me_text": "Ne me montre plus" }, "filters": { "show_more": "Voir plus", "show_less": "Afficher moins" }, "breadcrumbs": { "home": "Accueil", "create_account": "Créer un compte", "account": "Compte", "addresses": "Adresses" }, "item": { "remove": "Retirer l'objet" } }, "sections": { "header": { "top_header_login": "S'identifier", "top_header_register": "Registre", "top_header_wishlist": "Liste de souhaits", "register_dropdown": "Pas de compte? Créer un ici", "forgot": "Mot de passe oublié", "all_collection": "Toutes les collections", "world_wide_delivery": "Livraison à l'échelle mondiale", "shipping_text": "Livraison gratuite au Royaume-Uni sur des commandes de plus de 100 £", "hot_line": "Hot line" }, "menu": { "mobile_menu_tab": "Menu", "mobile_account_tab": "Compte", "mobile_settings_tab": "Paramètres" }, "slideshow": { "next_slide": "Diapositive suivante", "previous_slide": "Diapositive précédente", "pause_slideshow": "Mettre en pause le diaporama", "play_slideshow": "Jouer le diaporama", "play_video": "Lire la vidéo", "close_video": "Fermer la vidéo" }, "map": { "get_directions": "Obtenir des directions", "address_error": "Vous ne trouvez pas cette adresse", "address_no_results": "Aucun résultat pour cette adresse", "address_query_limit_html": "Vous avez dépassé la limite de Google utilisation de l'API. Envisager la mise à niveau à un régime spécial<\/a>.", "auth_error_html": "Il y avait un problème authentifier votre compte Google Maps . Créer et activer l'API JavaScript<\/a> et l'API de géocodage<\/a> les autorisations de application." } }, "blogs": { "article": { "view_all": "Voir toutes", "all_topics": "Tous les sujets", "by_author": "par [[ author ]]", "posted_in": "Publié dans", "read_more": "Plus", "back_to_blog": "Retour à [[ title ]]" }, "comments": { "title": "Laissez un commentaire", "name": "Nom", "email": "Courriel", "message": "Message", "post": "Publier le commentaire", "moderated": "Veuillez noter que les commentaires doivent être approvés avant d'être affichés", "success_moderated": "Votre commentaire a été soumis avec succès. Nous le publierons sous peu, suite à notre processus de modération.", "success": "Votre commentaire a été publié avec succès!", "comments_with_count": { "one": "[[ count ]] commentaire", "other": "[[ count ]] commentaires" } } }, "cart": { "general": { "title": "Panier", "note": "Ajouter une note à votre commande", "remove": "Retirer", "subtotal": "Sous-total", "savings": "Vous économisez", "shipping_at_checkout": "Frais de port et remises calculés à la caisse", "update": "Mettre à jour", "checkout": "Procéder au paiement", "empty": "Votre panier est vide.", "cookies_required": "Activer les cookies pour utiliser le panier", "cancel": "Annuler", "edit": "Éditer", "continue_shopping": "Continuer vos achats", "view_and_edit_cart": "Afficher et modifier le panier", "processing": "En traitement...", "items_count_label" : "[[ count ]] article(s) dans votre panier", "ok" : "D'accord", "empty_page_title": "Le panier d'achat est vide", "empty_continue_html": "Cliquer ici pour poursuivre vos achats.", "clear": "Vider le panier", "recently_added_item": "Article (s) récemment ajouté (s)", "remove_item": "Enlever cet article", "here": "ici" }, "label": { "product": "Produit", "price": "Prix", "quantity": "Quantité", "total": "Total", "total_item": "Total de l'élément", "sub_total_top": "Sous-total du panier" } }, "collections": { "general": { "view_all": "Voir toutes", "clear_all": "Tout Supprimer", "no_matches": "Aucun produit ne correspond à votre recherche.", "items_with_count": { "one": "[[ count ]] item", "other": "[[ count ]] items" }, "load_more": "Charger plus", "sidebar_btn": "Filtrer par" }, "sorting": { "title": "Trier par", "manual": "En vedette", "best_selling": "Meilleurs vendeurs", "title_ascending": "A-Z", "title_descending": "Z-A", "price_ascending": "Prix: faible à élevé", "price_descending": "Prix: élevé à faible", "created_descending": "Date: récent à ancien", "created_ascending": "Date: ancien à récent" }, "filters": { "title_tags": "Filtrer", "all_tags": "Tous les produits", "categories": "Les catégories", "title": "Filtre", "color": "Couleur", "size": "Taille", "brand": "Marque", "price": "Prix", "green": "Vert", "blue": "Bleu", "red": "Rouge", "pink": "Rose", "black": "Noir", "purple": "Violet", "white": "Blanc", "orange": "Orange" }, "product_item": { "quick_shop": "Aperçu rapide", "compare": "Comparer", "wishlist": "Ajouter à la liste de souhaits" } }, "contact": { "form": { "name": "Nom", "email": "Courriel", "phone": "Téléphone", "message": "Message", "submit": "Envoyer", "post_success": "Merci de nous avoir avoir contacté. Nous vous reviendrons le plus rapidement possible.", "address": "Adresse", "telephone": "Téléphone", "title": "Écrivez-nous", "required": "Requis" } }, "customer": { "account": { "title": "Mon compte", "details": "Détails du compte", "view_addresses": "Voir les adresses", "return": "Retour aux détails du compte" }, "activate_account": { "title": "Activer le compte", "subtext": "Créez votre mot de passe pour activer le compte.", "submit": "Activer le compte", "cancel": "Refuser l'invitation", "password": "Mot de passe", "password_confirm": "Confirmer le mot de passe" }, "addresses": { "title": "Votre adresse", "default": "Par défaut", "add_new": "Ajouter une nouvelle adresse", "edit_address": "Éditer l'adresse", "first_name": "Prénom", "last_name": "Nom", "company": "Compagnie", "address1": "Adresse 1", "address2": "Adresse 2", "city": "Ville", "country": "Pays", "province": "Province", "zip": "Code postal", "phone": "Téléphone", "set_default": "Définir comme adresse par défaut", "add": "Ajouter l'adresse", "update": "Mettre à jour l'adresse", "cancel": "Annuler", "edit": "Éditer", "delete": "Supprimer", "delete_confirm": "Êtes-vous certain(e) de vouloir supprimer cette adresse?" }, "login": { "title": "Connexion", "desc": "Si vous avez un compte, connectez-vous avec votre adresse e-mail.", "email": "Courriel", "password": "Mot de passe", "forgot_password": "Mot de passe oublié?", "sign_in": "Se connecter", "guest_title": "Continuer en tant qu'invité", "guest_continue": "Continuer" }, "orders": { "title": "Historique des commandes", "order_number": "Commande", "date": "Date", "payment_status": "Statut du paiement", "fulfillment_status": "Statut du traitement de la commande", "total": "Total", "none": "Vous n'avez pas placé de commande à ce jour." }, "order": { "title": "Commande [[ name ]]", "date": "Placée le [[ date ]]", "cancelled": "Commande annulée le [[ date ]]", "cancelled_reason": "Motif: [[ reason ]]", "billing_address": "Adresse de facturation", "payment_status": "Statut du paiement", "shipping_address": "Adresse de livraison", "fulfillment_status": "Statut du traitement de la commande", "discount": "Rabais appliqué", "shipping": "Livraison", "tax": "Taxes", "product": "Produit", "sku": "SKU", "price": "Prix", "quantity": "Quantité", "total": "Total", "fulfilled_at": "Traitée le [[ date ]]", "subtotal": "Sous-total" }, "recover_password": { "title": "Réinitialiser votre mot de passe", "email": "Courriel", "submit": "Soumettre", "cancel": "Annuler", "subtext": "Nous vous ferons parvenir un courriel pour réinitialiser votre mot de passe.", "success": "Nous vous avons fait parvenir un courriel pour réinitialiser votre mot de passe." }, "reset_password": { "title": "Réinitialiser le mot de passe du compte", "subtext": "Entrez un nouveau mot de passe pour [[ email ]]", "submit": "Réinitialiser le mot de passe", "password": "Mot de passe", "password_confirm": "Confirmer le mot de passe" }, "register": { "title": "Créer un compte", "first_name": "Prénom", "last_name": "Nom", "email": "Courriel", "submit": "Créer", "password": "Mot de passe", "desc": "La création d'un compte est simple. Remplissez le formulaire ci-dessous." } }, "homepage": { "onboarding": { "product_title": "Le nom de votre produit", "product_description": "Cette partie est utilisée pour la fiche du produit. Parlez aux clients de l'allure, du ressenti et du style de votre produit. Ajoutez des détails sur la couleur, les matériaux utilisés, le dimensionnement, et où il a été fabriqué.", "collection_title": "Le nom de votre collection", "blog_title": "Le titre de votre publication", "blog_excerpt": "Votre magasin n'a encore rien bloggué. Un blog peut être utilisé pour parler des lancements de nouveaux produits, d'astuces, ou d'autres nouvelles que vous voulez partager avec vos clients. Vous pouvez regarder le blog d'e-commerce de Shopify pour trouver de l'inspiration et des conseils pour votre propre magasin et blog.", "blog_author": "Nom de l'auteur", "no_content": "Cette section ne contient actuellement aucun contenu. Ajoutez-en en utilisant la barre latérale." } }, "layout": { "navigation": { "search": "Recherche", "toggle": "développer\/réduire", "expand": "révéler", "collapse": "fermer", "all_categories": "toutes catégories" }, "cart": { "title": "Panier", "items_count": { "one": "item", "other": "items" } }, "customer": { "account": "Compte", "log_out": "Se déconnecter", "logout": "Se déconnecter", "log_in": "Se connecter", "create_account": "Créer un compte", "sign_up": "S'inscrire", "wishlist": "Liste de souhaits" }, "footer": { "social_platform": "[[ name ]] sur [[ platform ]]" }, "list_page": { "grid": "La grille", "list": "Liste" } }, "products": { "product": { "regular_price": "Prix régulier", "sold_out": "Épuisé", "unavailable": "Non disponible", "on_sale": "Solde", "quantity": "Quantité", "add_to_cart": "Ajouter au panier", "back_to_collection": "Retour à [[ title ]]", "related_title": "Produits connexes", "qty_increase": "Augmenter", "qty_decrease": "Diminution", "deal_days": "Journées", "deal_hours": "Heures", "deal_minutes": "Minutes", "deal_second": "Seconde", "select_option": "Sélectionner une option", "add_to_wishlist": "Ajouter à la liste de souhaits", "add_to_review": "Ajouter à la critique", "first_review": "Soyez le premier avis", "compare_success_msg": "[[ product_title ]] a ajouté à la boîte de comparaison réussie", "compare_exist_msg": "[[ product_title ]] existe dans la boîte de comparaison", "compare_cart_msg": "[[ product_title ]] a ajouté à la liste de souhaits réussie", "compare_remove_msg": "[[ product_title ]] a été supprimé de la boîte de comparaison", "comparing_box": "Boîte de comparaison", "compare_no_items": "Il n'y a aucun élément dans la boîte de comparaison", "wishlist_success_msg": "[[ product_title ]] a ajouté à la liste de souhaits réussie", "wishlist_exist_msg": "[[ product_title ]] existe dans la liste de souhaits", "wishlist_cart_msg": "[[ product_title ]] a ajouté au panier", "wishlist_box": "Liste de souhaits", "wishlist_remove_msg": "[[ product_title ]] a été retiré de la liste de souhaits", "wislist_no_items": "Il n'y a aucun élément dans la liste de souhaits", "share": "Partager le produit", "share_on_facebook": "Partager sur Facebook", "share_on_twitter": "Partager sur Twitter", "share_on_pinterest": "Partager sur Pinterest", "share_on_google": "Partager sur Google+", "share_on_linkedin": "Partager sur LinkedIn", "availability": "Disponibilité", "in_stock": "En stock", "out_of_stock": "En rupture de stock", "quick_overview": "Rapide vue d'ensemble", "details": "Détails", "reviews": "Avis", "tags": "Tags du produit", "options": "Les options", "vendor": "Vendeur", "features": "Les traits", "size_chart": "Tableau des tailles", "sale_left_text":"[[ sales ]] VENDU. SE DÉPÊCHER! SEULEMENT QUELQUES GAUCHE!", "checkout_text": "Paiement sécurisé et approuvé avec" }, "upsell": { "recommend_text": "Quelqu'un a acheté un", "minute_ago": "il y a quelques minutes" } }, "gift_cards": { "issued": { "title_html": "Votre carte-cadeau [[ shop ]] d'une valeur de [[ value ]]!", "subtext": "Voici votre carte-cadeau!", "disabled": "Désactivée", "expired": "Expirée le [[ expiry ]]", "active": "Expire le [[ expiry ]]", "redeem_html": "Entrez ce code lors du paiement pour utiliser votre [[ value ]] carte-cadeau", "shop_link": "Boutique", "print": "Imprimer ce bon d'achat", "remaining_html": "[[ balance ]] restant", "add_to_apple_wallet": "Ajouter à Apple Wallet" } }, "date_formats": { "month_day_year": "%d %B, %Y" } } }